In a recent interactive online event, leading expert cardiologists and neurologists came together to discuss the clinical challenges in CV events and stroke.

Panellists Prof. Gilles Montalescot, Prof. Roberto Ferrari and Prof. Charlotte Cordonnier led the interactive case study reviews and then took part in a panel discussion with questions from participants.

Catch up on what the experts had to say in these three on-demand video replays and accompanying slides.

 

Clinical Takeaways

  • Identify Underlying Vessel Disease: When dealing with cases of intracerebral haemorrhage, it is crucial to recognize that bleeding caused by aspirin is a misconception. The primary focus should be on identifying the underlying vessel disease to accurately assess the balance between future hemorrhagic and ischemic risks

  • Strict Blood Pressure Control: In patients presenting with intracerebral haemorrhage, maintaining strict control of blood pressure is essential from admission to discharge. This approach significantly improves patient outcomes and reduces the risk of complications

  • Comprehensive Secondary Prevention: For patients at risk of cardiovascular events, consider a comprehensive approach to secondary prevention. Utilize statins, PCSK9 inhibitors, and ACE inhibitors, while being cautious about the use of ARBs

  • Effective Management of Transient Ischemic Attack (TIA): Rapid assessment and patient education are critical in cases of TIA, which is considered an emergency. For an accurate evaluation, recommended imaging includes MR and CT perfusion within 24 hours. Treatment involves using a combination of aspirin and clopidogrel for 21 days

Gilles Montalescot is Professor of Cardiology at the Pitié Salpêtrière Hospital in Paris, France, where he heads the Department of Cardiology at the Institute of Cardiology. He is a practicing Interventional Cardiologist and has extensive experience in basic and clinical research. He has been the director of the INSERM research Unit UMRS_1166 on Thrombosis for 10 years. Dr Montalescot has been an investigator for many of the new drugs developed in the past twenty years as well as for many of the new interventional technologies. Dr Montalescot is a senior scientist and has been the lead investigator of many national or international randomized trials including ADMIRAL, ARMADA, ALBION, STEEPLE, ARCHIPELAGO, ABOARD, ACAPULCO, ATOLL, ARCTIC, ANTARCTIC, ACCOAST, ATLANTIC, AEGEAN, AMERICA, ALBATROS, and the ongoing ATLANTIS, ALPHEUS, ARAMIS, ADRIFT trials. Dr Montalescot is the Chairman of the ACTION study group, an Academic Research Organization based at Pitié Salpêtrière Hospital in Paris. He has served on several task force committees on antithrombotic drugs and acute coronary syndromes and is the current Chairman of the Stable Coronary Artery disease guidelines of the European Society of Cardiology. Dr Montalescot has received several awards in his country including the J. Valade Prize from the Fondation de France and the J.Escalle award from the National Academy of Medicine. He is a member of several editorial boards and has published over 600 peer reviewed original articles in journals such as the NEJM, JAMA, Lancet. Internationally, Dr Montalescot has also been an invited speaker at plenary sessions of major congresses such as the European Society of Cardiology, the American College of Cardiology ,and the American Heart Association.

Prof. Roberto Ferrari currently holds the position of Emeritus Professor at the University of Ferrara, and Scientific Director of Medical Trial Analysis.

Prof. Ferrari has served as the Director of the Cardiovascular Centre of the University of Ferrara, the Director of Cardiology at the St. Anna University Hospital of Ferrara, and the Director of the Centre of Cardiovascular Research "S. Maugeri". Prof. Ferrari is past President of the European Society of Cardiology (ESC).

Prof Ferrari has contributed scientific findings targeted at characterizing the molecular mechanisms of the ischemic and failing myocardium, to improve the clinical treatment of myocardial ischemia and heart failure, while placing a particular emphasis on interdisciplinary and collaborative studies.

Prof. Charlotte Cordonnier, MD, PhD, is a neurologist specialised in stroke medicine. Appointed as Professor of Neurology at the Lille University (France) in 2012, she is the chair of the department of Neurology & Stroke centre of the Lille University Hospital.

Her research interests are intracerebral haemorrhages (including microbleeds) both in the setting of stroke and dementia, acute management of stroke, and stroke specificities in women. She is the director of the Lille Haemorrhagic Stroke research program inside the INSERM U1172. She is is a member of the task force between European Academy of Neurology and European Society of Cardiology. She currently serves as Associate Editor of the Stroke journal.

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