Medical oncologist at the Institut de Cancérologie de l’Ouest and a researcher in Team 7 of CRCI2NA. He is also affiliated with the PISTER programme of SIRIC ILIAD, dedicated to cellular oncology.

His research focuses on two main areas: circulating cancer biomarkers for the detection and characterisation of solid tumours through blood-based approaches, and epigenetics, specifically the mechanisms acquired by cancer cells over time and under treatment pressure.

His work aims to better understand treatment resistance and to develop epigenetic strategies to prevent or overcome it, with current research spanning brain tumours, gynecological cancers, and breast cancer.

Prof. Jean-Sebastien Frenel has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies: