204P ESMO Poster - NSCLC Patient and Caregiver Global Survey

We are pleased to share findings from a PRECISION ONCOLOGY CONNECT survey that were presented as a poster at ESMO 2024.

 

A group of international multidisciplinary clinical experts and Patient Advocacy Group representatives designed a global survey to assess the awareness and understanding of biomarker testing among patients with non-small cell lung cancer (NSCLC) and their caregivers. 

 

Varied levels of comprehension of biomarker testing among both people with NSCLC and caregivers can impede effective treatment decisions.

 

Therefore, as targeted therapies increasingly become the standard in treating NSCLC, understanding the engagement of patients and caregivers is essential to enhance physician-patient interactions for better care outcomes.  

 

 

Clinical takeaways

  • Patients with NSCLC and those in a caregiving capacity consider it important to know the biomarker test results, although few fully understand them 
  • Gaps exist in the delivery of accurate and clear communication regarding biomarker testing 
  • There is a need for healthcare teams to provide more effective communication strategies in this setting to improve healthcare access, outcomes, and advocacy for patients and caregivers 

Educational objectives

  • To define the level of awareness and understanding of biomarker testing amongst patients with non-small cell lung cancer (NSCLC) and their caregivers to identify the areas where additional education/support from healthcare professionals is required to improve the shared decision-making process.

Prof. Rolfo MD, PhD, MBA, Dr, is the Director Ohio State Division of Medical Oncology and Associate director  of Clinical Research at the Center for Thoracic Oncology, Tisch Cancer Institute in Mount Sinai System . In addition, he is Professor of Medicine at the Division of Hematology and Oncology at Icahn School of Medicine, Mount Sinai, New York, NY, USA. From April 2018 to May 2021 he was serving as Director of Thoracic Medical Oncology and Director of Early Clinical Trials at the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center (UMGCCC), in Baltimore, Maryland, USA. In addition, he was appointed Professor of Medicine at the Division of Oncology at Maryland University, School of Medicine. Prof. Rolfo is Medical Oncologist focused in Thoracic Oncology, Drug Development and Translational Oncology. From 2012 to March 2018 he was working as Director of the Phase I - Early Clinical Trials Unit, Director of the Clinical Trials Management Program at Antwerp University Hospital, and Senior Staff member of Thoracic Oncology Cluster at Antwerp University Hospital in Belgium. In addition he is Professor of Oncology at Antwerp University in the Center for Oncological Research (CORE) in Antwerp, Belgium, Professor Rolfo graduated with a degree in medicine from the National University of Córdoba, Argentina in 1996; he then studied at the University of Milan and the National Cancer Institute of Milan, Italy, receiving European Oncology Board certification in 2003, followed by Spanish Board Certification in Medical Oncology in 2007. He obtained a PhD and Doctor Europaeus in Clinical and Experimental Oncology Research cum laude from the University of Palermo, Italy in 2009 under the direction of Professor Rosell, and a Master of Business Health Administration from the Polytechnic University of Valencia, Spain in 2010. He worked as clinical researcher in the Spanish Lung Cancer Group in Mallorca, Spain for 8 years. He is actively working on drug development and Lung cancer & Mesothelioma treatment. His research is focused in molecular oncology and Immunotherapy in Thoracic Oncology and in a pan-tumoral approach, using new techniques in liquid biopsies, specifically in exosome isolation and circulating free tumour DNA. His group identify ALK translocation in exosomes in NSCLC patients, showed, for the first time, the videos of labeled EVs uptake by living lung cancer cells. He is currently working in the identification of new biomarkers involved in immunotherapy and TKI drug-resistance. In Drug development Prof. Rolfo contributed to the development of several compounds including Erlotinib, pharmacokinetics of Olaparib, Entrectinib among several drugs in early phase.

Prof. Christian Rolfo has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

Archer Dx, AstraZeneca, BMS, Boston Pharmaceuticals, Blueprint, Eisai, Inivata, Guardant Health, MD Serono, Mirati, MSD, Novartis, Pfizer and Roche.

 

Fernando Lopez-Rios is the Chief of the Molecular Diagnostics Service at Hospital Universitario 12 de Octubre (Madrid) and Professor of Pathology at Universidad Complutense (Madrid).

 

Dr Lopez-Rios has also been the Director of the Therapeutic Targets Laboratory at HM Hospitales (Spain) and a visiting researcher at Memorial Sloan Kettering Cancer Center (New York).

 

He is the 2023 recipient of the Mary J. Matthews Pathology & Transitional Research Award (International Association for the Study of Lung Cancer, IASLC) and the Deputy Chair of the IASLC Pathology Committee.

 

His main clinical and research expertise is in cancer biomarker testing.

Prof. Fernando López-Ríos, MD, PhD has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

AstraZeneca, Bayer, BMS, Lilly, MSD, Pfizer, Roche, Takeda and Thermo Fisher. 

 

Rodrigo Paredes de la Fuente, MD is a Resident Physician at Mount Sinai West/Morningside and a researcher at the Icahn School of Medicine at Mount Sinai. He earned his medical degree from Universidad San Martín de Porres in Lima, Peru. Following medical school, he completed a research fellowship at Beth Israel Deaconess Medical Center at Harvard Medical School in Boston, where his work focused on genomic profiling and precision oncology for pancreatic and
hepatobiliary tumors.
 
Rodrigo is actively involved in research within the Thoracic Oncology Department, with a particular interest in liquid biopsies and their role in guiding diagnosis and management for lung cancer patients. He has also contributed to projects advancing awareness of genomic testing and its benefits for patients.
 
His research has been presented at prominent conferences, including the American Society of Clinical Oncology Annual Meeting and the European Society
for Medical Oncology Congress, and he has co-authored several peer-reviewed publications. In 2024, Rodrigo was honored with the ASCO Annual Meeting
Research Award for his work on the impact of mutations in lung cancer progression and received an educational award from the International Association for the Study of Lung Cancer for his research on the impact of liquid biopsies in EGFR mutant lung cancer.
 
Rodrigo’s work is driven by a dedication to improving patient outcomes through cutting-edge research in precision oncology.
 

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PRECISION ONCOLOGY CONNECT is an initiative of COR2ED, supported by Independent Educational Grants from AstraZeneca, Amoy Diagnostics, Bayer, Pierre Fabre Laboratories and Thermo Fisher Scientific.

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LUNG CONNECT is an initiative of COR2ED, supported by Independent Educational Grants from Bayer, Pierre Fabre Laboratories and Boehringer Ingelheim.

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