Prof. Charlie Gourley

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Medical Oncologist

  • CRUK Edinburgh Centre, Nicola Murray Centre for Ovarian Cancer Research
  • location United Kingdom

Professor of Medical Oncology and Honorary Consultant in Medical Oncology; Clinical Director, CRUK Scotland Centre; Director, Nicola Murray Centre for Ovarian Cancer Research

Charlie graduated in Genetics and Medicine from Glasgow University in 1991 and 1994 respectively. From 1998 to 2005, he trained in medical oncology in Edinburgh, during which time he was awarded a PhD in ovarian cancer genetics from the University of Edinburgh and an NHS Education for Scotland Clinician Scientist Award. He was appointed as Senior Lecturer in Medical Oncology at the University of Edinburgh in 2005, Reader in Medical Oncology in 2011 and Professor of Medical Oncology (Personal Chair) in 2012. He received a Scottish Senior Clinical Fellowship Award in 2010. He became Director of the Nicola Murray Centre for Ovarian Cancer Research in 2016, Clinical Director of the Cancer Research UK Edinburgh Centre in 2019 and Clinical Director of the Cancer Research UK Scotland Centre in 2022.

Charlie’s clinical research focus is ovarian cancer clinical trials. He was UK Lead for the SOLO1 trial, which led to the first-line licence for olaparib in BRCA-mutant ovarian cancer, and for the GOG281/LOGS trial of trametinib, which is the first positive randomised controlled trial in low-grade serous ovarian cancer.

Charlie’s translational research focuses on molecular characterisation of ovarian cancer in order to improve understanding of drug sensitivity and resistance. His current priorities include targeting the molecular subgroups revealed by whole genome sequencing of high grade serous ovarian cancer and discovering new therapeutic strategies for treatment of low grade serous ovarian cancer.

Prof. Charlie Gourley has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

AstraZeneca, Apera, Clovis, MSD, Nucana, Novartis, Roche, Sierra Oncology and Tesaro. 

Programmes developed by Prof. Charlie Gourley

eks
Experts Knowledge Share Video
Oncology 
HER2 testing: The evolving role of immunohistochemistry (IHC)

Best practices and interpretation of results in lung and ovarian cancer 

Experts
Prof. Fernando López-Ríos, MD, PhD, Prof. Christian Rolfo, Prof. Charlie Gourley
Endorsed by
Exon20group ICAN international cancer advocacy network Biomarker Collaborative
  • download Downloadable
    Resources
  • clock 77 MIN
  • calendar Mar 2025

Educational programme supported by an Independent Educational Grant from AstraZeneca.
Oncology 
PARP inhibition and DNA Damage Response (DDR)

This comprehensive resource looks at PARP inhibition and DDR as therapeutic targets across multiple tumour types

Experts
Prof. Simon Boulton, Dr Violeta Serra, Dr Judith Balmaña, Prof. Charlie Gourley
  • clock 30 MIN
  • calendar Oct 2021

This educational programme is supported by an Independent Educational Grant from AstraZeneca
other Other
Oncology 
The Role of DDR and PARP inhibition (PARPi) in Oncology – BluePrints

Experts
Dr Violeta Serra, Prof. Jonathan A. Ledermann, Prof. Eric Pujade-Lauraine, Prof. Simon Boulton, Dr Mark J. O'Connor, Prof. Charlie Gourley, Dr Judith Balmaña, Prof. Sibylle Loibl
  • download Downloadable
    Resources
  • clock MIN
  • calendar Sep 2021

This educational programme is supported by an Independent Educational Grant from AstraZeneca
Oncology 
Moving from PARP Inhibition to Targeting DNA Repair and DDR in Cancer Therapy

Experts
Dr Judith Balmaña, Dr Rebecca Dent, Prof. Simon Boulton, Prof. Sibylle Loibl, Prof. Eric Pujade-Lauraine, Prof. Charlie Gourley, Dr Violeta Serra, Prof. Jonathan A. Ledermann
  • download Downloadable
    Resources
  • clock 10 MIN
  • calendar Sep 2021

This educational programme is supported by an Independent Educational Grant from AstraZeneca
Oncology 
An Experts’ Forum in Tokyo and Singapore on DDR and PARP inhibition

Experts
Prof. Keiichi Fujiwara, Prof. Simon Boulton, Dr Shinji Ohno, Dr Rebecca Dent, Prof. Charlie Gourley
  • download Downloadable
    Resources
  • clock 60 MIN
  • calendar Sep 2021

This educational programme is supported by an Independent Educational Grant from AstraZeneca