Pediatric and Adolescent Medicine
From the start of his academic career, Prof. Dr. Joachim Woelfle had a major interest in growth disorders. During his residency in Bonn, Prof. Dr. Woelfle started his scientific education as the head of a junior research group, trying to elucidate the role of pulsatile growth hormone release on gene transcription. This was followed by a 3-year postdoc timeout at OHSU in Oregon, where he mainly worked on GH-receptor-induced signalling, which led to the biochemical identification of Stat5b as a main regulator of IGF-1 gene transcription. This was soon followed by the identification of a first patient with GHIS, harbouring a Stat5b mutation, by Vivien Hwa and Ron Rosenfeld. Since then, Prof. Dr. Woelfle’s main clinical and research interests focused on growth disorders, first as head of pediatric endocrinology division at the university of Bonn, Germany; since 2019 as the chair of pediatrics at the university of Erlangen.
Video podcast exploring primary IGF-I deficiency, GH deficiency and other rare growth disorders