Many HCPs come into contact with patients with bleeding disorders like von Willebrand disease (VWD) or haemophilia. In this short animated video, guided by haematologists Dr Vickie McDonald and Prof. Ana Boban, you'll learn about:
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Differences between primary and secondary haemostasis
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The importance of interpreting laboratory coagulation
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Consequences of the deficiencies in the coagulation cascade for von Willebrand disease and haemophilia A
Clinical Takeaways
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Inherent bleeding disorders may be difficult to recognize and diagnose; better understanding of the primary and secondary haemostasis can ensure proper diagnosis and optimized care of those affected
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Clotting time tests are useful tools to recognize and diagnose people with a potential bleeding disorder; consult a haematologist when in doubt
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Patients with VWD may have normal PT and aPTT values, where more severe VWD can result in a prolonged aPTT due to low factor VIII levels; patients with haemophilia A have a prolonged aPPT value due low activity of factor VIII