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TRK fusion-positive cancer poster tour at ESMO 2022

TRK fusion-positive cancer poster tour at ESMO 2022

Prof. David Hong

NTRK CONNECT partnered with NTRKers on a poster tour at ESMO 2022. Led by Prof. David Hong, the tour provided patients and caregivers an opportunity to better understand the latest TRK fusion-positive cancer data, with a particular emphasis on lung cancer.

Video summaries of 2 abstracts from ESMO 2022 and 1 abstract from WCLC 2022 are available to view now.

Prof. David Hong

Medical Oncologist

MD Anderson Cancer Center, Houston

United States (US)

Biography Disclosures

Prof. David Hong

Medical Oncologist

MD Anderson Cancer Center, Houston

United States (US)

Dr David S. Hong is a Professor, Deputy Chairman in the Department of Investigational Cancer Therapeutics (Phase I Program), Clinical Medical Director of the Clinical Translational Research Center (CTRC), and Associate Vice President of Clinical Research at The University of Texas MD Anderson Cancer Center.

Dr Hong was instrumental in forming one of the largest and most innovative Phase 1 clinical trial units in the world, with over 1300 patients enrolled in clinical trials in FY2021 and over 400 active ongoing clinical trials.

Dr Hong has been the Principal Investigator of over 120 research protocols that involve a wide range of sponsors, including the Cancer Therapy Evaluation Program (CTEP) at the National Cancer Institute. He has published over 374 publications in Peer-reviewed Journals such as NEJM, Lancet Oncology, JCO and Nature.

He has been involved in the early development of cabozantinib, siltuximab, dabrafenib, trametinib, regorafenib, lenvatinib, larotrectinib, tesotumab vendotin, and sotorasib the first drug to target KRAS that have led to FDA approval.

He has also helped found 2 companies OncoResponse and Telperian.

He is an expert on c-Met, NTRK, KRAS, and adoptive cellular therapy in solid tumors and has led several national trials such as the c-Met amplified, c-Met exon 14 deleted, and NTRK arms of the NCI-MATCH trial. He been awarded the ASCO Young Investigator Award, the Jesse Jones award, Best Boss award at MD Anderson, Irwin Krakoff Award for Clinical Research, and the Gerald P. Bodey award for education and Mentor of the year award in the Division of Cancer Medicine, MD Anderson.

Prof. David Hong has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

AbbVie, Adaptimmune, Adlai-Nortye, Amgen, Astra-Zeneca, Bayer, Bristol- Myers Squibb, Daiichi-Sankyo, Deciphera, Eisai, Endeavor, Erasca, F. Hoffmann- LaRoche, Fate Therapeutics, Genentech, Genmab, Ignyta, Infinity, Kite, Kyowa Kirin, Lilly, LOXO, Merck, Medimmune, Mirati, Mologen, Navier, NCI-CTEP, Novartis, Numab, Pfizer, Pyramid Bio, SeaGen, Takeda, TCR2, Teckro, Turning Point Therapeutics and VM Oncology.

Poster 1: Dufresne A. et al (ESMO 2022)

time | open 1 min | Oct 2022

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Poster 2: McDermott R. et al (ESMO 2022)

time | open 2 min | Oct 2022

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Poster 3: Moreno V. et al (WCLC 2022)

time | open 2 min | Oct 2022

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I agree that this educational programme:

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The three posters covered are:

Poster 1 - Larotracking - Real life study of locally advanced/metastatic solid tumor treated with larotrectinib in French expanded access program (Dufresne A. et al)
Poster 2 - Efficacy and safety of larotrectinib in a pooled analysis of patients with tropomyosin receptor kinase fusion cancer with an extended follow-up (McDermott R. et al)
Poster 3 - Extended follow-up of efficacy and safety of larotrectinib in patients with TRK fusion lung cancer (Moreno V. et al)

PRECISION ONCOLOGY CONNECT is an initiative of COR2ED, supported by an Independent Educational Grant from AstraZeneca and Bayer.

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