Understand the mechanism of action of PARP inhibitors and targeting DNA Damage Response (DDR): A short video

Developed by international experts in DDR and PARP inhibition, this short video succinctly explains the concept of DDR, including the role of Homologous Recombination Repair (HRR) in DNA repair and the impact of BRCA1 and BRCA2 mutations. It looks at PARP inhibitors as the proof of concept for targeting DDR, demonstrating how they work and their clinical benefit.
 
Watch the full video below or use the scroll-bar at the side or below the video to select the chapter that interests you most.
 
To download the videos for your own use, please follow the link to vimeo, there you can select the option download the video.

Introduction

DNA Damage Response (DDR)

Mechanism of Action of PARP inhibitors

Clinical Benefit of PARP inhibitors

The Future of PARP inhibition and Targeting DDR


The video is also available to view and download in chapters, please follow the links below to vimeo, there you can select the option download the video: