Understand the mechanism of action of PARP inhibitors and targeting DNA Damage Response (DDR): A short video

Developed by international experts in DDR and PARP inhibition, this short video succinctly explains the concept of DDR, including the role of Homologous Recombination Repair (HRR) in DNA repair and the impact of BRCA1 and BRCA2 mutations. It looks at PARP inhibitors as the proof of concept for targeting DDR, demonstrating how they work and their clinical benefit.

Watch the full video below or use the scroll-bar at the side or below the video to select the chapter that interests you most.

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AstraZeneca has provided a sponsorship grant towards this independent programme.