In this on-demand Tweetorial video from BREAST CANCER CONNECT, esteemed expert Dr Aditya Bardia presents a patient with ER+/HER2-low metastatic breast cancer, exploring the entire diagnostic and treatment process.

 

This is the second Tweetorial in a series on breast cancer management. Catch up on the first video to hear Dr Paolo Tarantino present a patient case with ER+/HER2- de novo metastatic breast cancer. 

 

Clinical Takeaways

  • Elacestrant improves PFS vs SOC in patients with ESR1m, irrespective of PIK3CAm or HER2-low status

  • Hyperglycemia is a target side effect of the PIK3CA inhibitors and needs to be monitored closely

  • T-DXd can be considered for patients with HER2-low mBC after ≥1 line of ChT

Dr Aditya Bardia, a board-certified medical oncologist, is an Attending Physician at Massachusetts General Hospital (MGH), Associate Professor, Harvard Medical School, Boston. As the Director of Breast Cancer Research Program at MGH, Dr Bardia is interested in advancing research to improve the outcomes with breast cancer. Dr Bardia has led the clinical development of antibody drug conjugate (ADC), sacituzumab govitecan, the first ADC approved for patients with metastatic triple negative breast cancer. Dr Bardia has received several research awards including outstanding award for research excellence at Mayo Clinic, Young Investigator Award from ASCO, and Douglas Family Foundation prize for excellence in oncology research at MGH. Dr Bardia is the editor of precision medicine clinic section of The Oncologist, co-leader of the Molecular and Precision (MAP) tumor board at MGH, and editorial board member of ASCO molecular oncology tumor board.

Dr Aditya Bardia has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

Consultant/Advisory board: Pfizer, Novartis, Genentech, Merck, Radius Health, Immunomedics/Gilead, Sanofi, Daiichi Pharma/Astra Zeneca, Eli Lilly, Mersana. Contracted Research/Grant (to institution): Genentech, Novartis, Pfizer, Merck, Sanofi, Radius Health, Immunomedics/Gilead, Daiichi Pharma/Astra Zeneca, Eli Lilly.

Programme summary
  • clock Duration 11 MIN
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This educational programme is supported by an Independent Medical Education Grant from Menarini Stemline Oncology.
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BREAST CANCER CONNECT is an initiative of COR2ED, supported by an Independent Medical Educational Grant from Menarini Stemline Oncology.

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