Currently is the Chair of Predictive Molecular Pathology Laboratory, Department of Public Health of University Federico II of Naples and serves as Scientific Secretary of the International Society of Liquid Biopsy and Editor in Chief of The Journal of Liquid Biopsy.

His main research interest is in the field of genomic biomarkers validation and testing for predictive information in the field of lung cancer, metastatic colorectal cancer, melanoma and gastrointestinal stromal tumour.

Moreover, he has developed skills in tailoring Next Generation Assays for several different applications with a special focus on the simultaneously detection of clinically relevant alterations (i.e., EGFR mutations, ALK translocation, PD–L1 expression) in the routine setting including handling of different sample types, such as tissues and/or liquid biopsy specimens.

Assoc. Prof. Umberto Malapelle has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies: