Advancements in molecular testing have changed the diagnostic landscape in oncology, including the role of liquid biopsy as a testing method.

 

In this clinical topic video, molecular pathologist Assoc. Prof. Umberto Malapelle shares his insights into exactly how the role of liquid biopsy in precision oncology is evolving. He discusses the clinical application of liquid biopsies across the cancer patient journey, with a focus on non-small cell lung cancer (NSCLC), breast cancer and colorectal cancer.

 

 

Clinical takeaways

  • Liquid biopsies offer a less invasive alternative to traditional tissue biopsies and can be used to test the molecular landscape for patients with any solid tumour 
  • The role of liquid biopsy should be seen as a complementary testing method to tissue based assays and the information derived should be reviewed in combination with tissue results 
  • The clinical application of liquid biopsies ranges from screening and diagnosis, treatment guidance, monitoring minimal residual disease to assessing chemotherapy resistance 

The evolving role of liquid biopsy

Educational objectives

 

Upon completion of this activity, the learner will: 

  • Know the latest developments and practical recommendations on the role of liquid biopsy in precision oncology, and how to apply this across the patient journey 

Currently is the Chair of Predictive Molecular Pathology Laboratory, Department of Public Health of University Federico II of Naples and serves as Scientific Secretary of the International Society of Liquid Biopsy and Editor in Chief of The Journal of Liquid Biopsy.

His main research interest is in the field of genomic biomarkers validation and testing for predictive information in the field of lung cancer, metastatic colorectal cancer, melanoma and gastrointestinal stromal tumour.

Moreover, he has developed skills in tailoring Next Generation Assays for several different applications with a special focus on the simultaneously detection of clinically relevant alterations (i.e., EGFR mutations, ALK translocation, PD–L1 expression) in the routine setting including handling of different sample types, such as tissues and/or liquid biopsy specimens.

Programme summary
Watch the video now
Share this programme
This educational programme is supported by an Independent Educational Grant from Bayer.
Endorsement
I agree that this educational programme:

Was valuable to me

1/4
Brought to you by
PRECISION ONCOLOGY CONNECT

PRECISION ONCOLOGY CONNECT is an initiative of COR2ED, supported by Independent Educational Grants from AstraZeneca, Amoy Diagnostics, Bayer and Pierre Fabre.

Meet the experts

Other programmes of interest

other Other
Oncology 
Biomarker testing in NSCLC: patient and caregiver awareness and understanding

Findings from a global survey presented in a poster at ESMO 2024

Experts
Prof. Christian Rolfo, Prof. Fernando López-Ríos, Dr. Rodrigo Paredes, Amy Moore, Anne-Marie Baird, Shani Shilo
Endorsed by
LUNGevity
Lung Cancer Europe IASLC
The Israeli Lung Cancer Foundation ISLB
  • download Downloadable
    Resources
  • clock 5 MIN
  • calendar Sep 2024

Educational programme supported by an Independent Educational Grant from Bayer.
podcast Podcast
  • download Downloadable
    Resources
  • clock 23 MIN
  • calendar Sep 2024

Educational programme supported by an Independent Educational Grant from Ipsen
conference-update Conference update
Oncology 
ESMO 2024: New data on GI, lung, HCC, breast and GU cancers

Renowned medical experts share their insights into new data presented at ESMO 2024

  • download Downloadable
    Resources
  • clock 3 MIN
  • calendar Sep 2024

animated-video Animated Video

Episode

1

of 1

episode
Oncology 
Precision oncology in prostate cancer: tips for optimal genomic testing

From sample collection through to diagnostic modalities 

Experts
Dr Alexander Wyatt
Endorsed by
AMP
  • download Downloadable
    Resources
  • clock 5 MIN
  • calendar Sep 2024

Educational programme supported by an Independent Educational Grant from AstraZeneca and Amoy Diagnostics.
video Video
Oncology Hemato-oncology 
Early relapsed/refractory multiple myeloma (RRMM): best practices in management

A 3-part video series on managing early RRMM from leading medical experts

Experts
Dr Elena Zamagni, Dr Fredrik Schjesvold, Dr Joseph Mikhael
  • download Downloadable
    Resources
  • clock 4 MIN
  • calendar Sep 2024

Educational programme supported by an Independent Educational Grant from Menarini Stemline Oncology.
other Other

Episode

2

of 2

episode
Oncology 
Optimising samples for biomarker testing in lung, prostate and gastric cancer

Recommendations for best practice

Experts
Dr Alexander Wyatt, Prof. Frédéric Bibeau
Endorsed by
AMP
  • download Downloadable
    Resources
  • clock 5 MIN
  • calendar Aug 2024

Educational programme supported by an Independent Educational Grant from AstraZeneca and Amoy Diagnostics.