Assoc. Prof. Tanya B. Dorff looks into the use of imaging along with the treatment of oligometastatic prostate cancer


Treating oligometastatic prostate cancer

Assoc. Prof. Tanya B Dorff examines the influence of imaging techniques on treatment of oligometastatic prostate cancer. In this video and accompanying slides, she defines oligometastatic prostate cancer before addressing imaging techniques as a critical component to successful treatment of oligometastatic prostate cancer.

Imaging in identifying and treating oligometastatic prostate cancer

Oligometastatic prostate cancer needs to be correctly identified to aid treatment decisions. Explored here are different imaging techniques such as CT, MRI, PET, or combined techniques. Discussed is the importance of imaging to correctly identify oligometastatic patients and high-volume patients. Data is presented examining the sensitivity of novel imaging PET tracers.

Targeted radiation in the treatment of oligometastatic metastases

Metastasis-directed therapy improves overall survival, as shown in the SABR-COMET clinical trial which looks at Stereotactic Ablative Radiotherapy (SABR), a technique that delivers high doses of radiation to small tumour targets for the treatment of oligometastatic metastases. Prof. Dorff presents and examines data from the SABR-COMET trial. Addressed are issues that need to be examined in future trials, and questions being answered by ongoing trials. Prof. Dorff surmises the ways in which imaging allows for identification and successful treatment of oligometastatic prostate cancer in an innovative metastasis-directed way. This video and slide-set have been designed as a useful educational resource for medical oncologists, and we hope you find them useful to your own clinical practice.

Following a residency at Mt. Sinai Hospital in New York City, Dr Dorff came to LAC + USC Medical Center for her hematology and medical oncology fellowship. She currently heads the Genitourinary group within the Department of Medical Oncology at the City of Hope Comprehensive Cancer Center. In addition to being a devoted clinician and translational researcher, Dr Dorff has authored more than 45 peer reviewed articles as well as 35 review articles/commentaries. Dr Dorff serves as an associate editor for Clinical Genitourinary Cancer and Seminars in Urologic Oncology. She has lectured on prostate and bladder cancer treatment nationally and internationally and has presented her research at national meetings. Current research interests include the effects of fasting on chemotherapy side effects and cancer control and immunotherapy for prostate cancer. She has been the principal investigator for more than a dozen clinical trials, involving targeted therapy and immunotherapy, for genitourinary cancers.

Assoc. Prof. Tanya Dorff has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

AstraZeneca, Astellas, Exelixis, Janssen and SeaGen.

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