Oncology Conference update

ASCO 2024 breast cancer highlights

How could the data impact clinical practice?

Prof. Shaheenah Dawood

Prof. Shaheenah Dawood
Publication Date

Jun 2024

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In this conference update video, Prof. Shaheenah Dawood joins us from ASCO 2024 to share her insights into new key breast cancer trial data from the DESTINY-Breast06, postMONARCH and INAVO120 trials and the potential impact on clinical practice.

 

ASCO 2024 selected breast cancer abstracts

  • Trastuzumab deruxtecan vs physician’s choice of chemotherapy in patients with HR+, HER2-low or HER2-ultralow metastatic breast cancer with prior endocrine therapy: Primary results from DESTINY-Breast06 (DB-06).
    Curigliano G, et al.
    Abstract LBA1000, ASCO 2024
  • Abemaciclib plus fulvestrant vs fulvestrant alone for HR+, HER2- advanced breast cancer following progression on a prior CDK4/6 inhibitor plus endocrine therapy: Primary outcome of the phase 3 postMONARCH trial.
    Kalinsky K, et al.
    Abstract LBA1001, ASCO 2024
  • First-line inavolisib/placebo + palbociclib + fulvestrant in patients with PIK3CA-mutated, HR+, HER2‑negative locally advanced/metastatic breast cancer who relapsed during/within 12 months of adjuvant endocrine therapy completion: INAVO120 Phase 3 randomized trial additional analyses.
    Juric D, et al.
    Abstract #1003, ASCO 2024

 

Shaheenah Dawood is a Consultant medical oncologist and professor in clinical oncology in the United Arab Emirates. She trained in medical oncology at McGill University Hospitals in Canada and subspecialized in breast cancer management at MD Anderson Cancer Center. During her training she was awarded multiple scholar in training awards and ASCO merit awards. She has served as an editorial fellow at the New England Journal of medicine and has an MPH from the Harvard School of Public Health. She has over 100 papers to her credit including 50 peer review original articles, 30 review articles and 12 book chapters. She serves as a reviewer for multiple journals. She currently leads the oncology clinical trials program at Mediclinic City Hospital Dubai. She also serves as president of the Excellence in oncology summit that is held annually in Dubai and is co president of the Asia pacific breast cancer summit (ABCS) and Asia pacific gastrointestinal cancer summit (APGCS). She has also recently launched the international BRCA forum and young womens forum.

Prof. Shaheenah Dawood has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

MSD, Roche, BMS, New Bridge, Novartis, llilly , Pfizer, Caris, Merck, Jaansen, Ipsen,Astrazeneca, Zulleg Pharma
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