In a recent interactive webinar, renowned experts Prof. Fernando López-Ríos, Assoc. Prof. Alicia Morgans and Assoc. Prof. Herbert Loong came together to explore precision oncology in practice for lung and prostate cancer.

 

Watch the on-demand video to hear the medical experts discuss how to address pre-analytical phase challenges during molecular testing, and the relevant biomarkers and tests to request for lung and prostate cancer patients.

 

Topics of conversation included:

  • An overview of common challenges related to biomarker testing across all tumour types
  • Challenges and considerations of biomarker testing for lung and prostate cancer throughout the patient journey

The event concluded with speakers and participants engaging in a Q&A to address pressing questions.

 

Watch the video replay and download the accompanying slides for your reference, then take the e-learning to earn a CME credit (access the e-learning using the red button on the right of your screen. Or, if you're reading this on mobile, you can find the e-learning and additional resources using the red arrow on the top right of this page).

 

Not got time to watch the full video? Go to the video highlights: Highlights: Precision oncology in practice- testing through to treatment in lung and prostate cancer.

 

Clinical Takeaways

  • Molecular testing with next-generation sequencing of DNA and RNA should be considered standard of care where possible using high-quality, sufficient tissue samples for accurate biomarker testing
  • Pathologists should conduct ‘reflex testing’ after histologic diagnosis of lung cancer, and liquid biopsies should be utilised as a complementary testing method or when tumour tissue is not feasible
  • Germline and somatic genetic testing in advanced prostate cancer may identify patients with HRR mutations and MSI-H who could be suitable for highly effective targeted agents
  • Multidisciplinary team or molecular tumour board discussion can facilitate interpretation of biomarker data, leading to more accurate patient stratification, treatment selection, and clinical decision-making

Educational objectives

  • Know how to address pre-analytical phase challenges and how to collect, store, process and prepare the samples
  • Have an awareness of which biomarkers and tests to request
  • Understand the diagnostic modalities and the role of biomarkers in oncology
  • Be able to implement or improve the leading role of the pathologist on the MDT 

Fernando Lopez-Rios is the Chief of the Molecular Diagnostics Service at Hospital Universitario 12 de Octubre (Madrid) and Professor of Pathology at Universidad Complutense (Madrid).

 

Dr Lopez-Rios has also been the Director of the Therapeutic Targets Laboratory at HM Hospitales (Spain) and a visiting researcher at Memorial Sloan Kettering Cancer Center (New York).

 

He is the 2023 recipient of the Mary J. Matthews Pathology & Transitional Research Award (International Association for the Study of Lung Cancer, IASLC) and the Deputy Chair of the IASLC Pathology Committee.

 

His main clinical and research expertise is in cancer biomarker testing.

Prof. Fernando López-Ríos, MD, PhD has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

AstraZeneca, Bayer, BMS, Lilly, MSD, Pfizer, Roche, Takeda and Thermo Fisher. 

 

Dr Morgans is Genitourinary Medical Oncologist at Dana-Farber Cancer Institute, and Faculty in Medicine at Harvard Medical School in Boston, MA. She completed medical school and residency at the University of Pennsylvania School of Medicine, fellowship in Hematology/Oncology at Harvard’s Dana Farber Cancer Institute and Massachusetts General Hospital Cancer Center in Boston and earned a Master of Public Health at Vanderbilt University. Dr Morgans treats patients with prostate, bladder, and testicular cancer, and her research assesses complications of advanced prostate cancer survivorship and patient-centered treatment decision-making in advanced prostate cancer.

Assoc. Prof. Alicia Morgans has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

AAA, Astellas, AstraZeneca, Bayer, Exelixis, Janssen, Myovant, Novartis, Pfizer, Sanofi and Telix. 

Dr Herbert H. Loong holds conjoint appointments of Clinical Associate Professor in the Department of Clinical Oncology and Deputy Medical Director of the Phase 1 Clinical Trials Centre of The Chinese University of Hong Kong.

 

Dr Loong obtained his medical degree with a Distinction in Surgery from The University of Hong Kong in 2003. He has completed a Fellowship in Drug Development at Princess Margaret Cancer Centre in Toronto, Canada with a focus on Experimental Therapeutics. His clinical and research interests include Thoracic Oncology, Sarcoma Medical Oncology and Health Economics.

 

Dr Loong is a recipient of the European Cancer Congress Fellowship Grant (2013), the American Society of Clinical Oncology (ASCO) Annual Meeting Merit Award (2014), the Hong Kong College of Physicians Young Investigators’ Award (2014). Dr. Loong led the Lung Cancer Team at CUHK to be bestowed the IASLC Foundation Cancer Care Team Award in recognition for providing the best thoracic oncology care in “Asia & Rest of the World” in 2018.

 

In recent years, Dr Loong has co-founded the Asia Pacific Oncology Drug Development Consortium (APODDC) and the Asia Pacific Coalition Against Lung Cancer (APCLC).

 

Dr Loong has served or continues to serve in various capacities in various professional international oncology bodies, including the International Affairs Committee and the Asia-Pacific Regional Council of ASCO, the Membership, Education and Communications Committees of the IASLC. He is the incoming Chairman of the International Affairs Committee of ASCO in 2024. He has been elected as a Board Member of the Connective Tissue Oncology Society (CTOS) for 2022-2024. In his prior appointment as a member of Pharmacy and Poisons Board of Hong Kong, he oversaw the registration of medicinal products and clinical trials in the territory.

Dr Herbert H. Loong has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

AbbVie, Amgen, Bayer, Boehringer-Ingelheim, Celgene, Eisai, Eli-Lilly, George Clinical, Guardant Health, Illumina, Janssen, Novartis, Merck Sereno, Pfizer, Takeda

In a recent interactive webinar, renowned experts Prof. Fernando López-Ríos, Assoc. Prof. Alicia Morgans and Assoc. Prof. Herbert Loong came together to explore precision oncology in practice for lung and prostate cancer.

 

Watch the on-demand video to hear the medical experts discuss how to address pre-analytical phase challenges during molecular testing, and the relevant biomarkers and tests to request for lung and prostate cancer patients.

 

Topics of conversation included:

  • An overview of common challenges related to biomarker testing across all tumour types
  • Challenges and considerations of biomarker testing for lung and prostate cancer throughout the patient journey

The event concluded with speakers and participants engaging in a Q&A to address pressing questions.

 

Watch the video replay and download the accompanying slides for your reference, then take the e-learning to earn a CME credit (access the e-learning using the red button on the right of your screen. Or, if you're reading this on mobile, you can find the e-learning and additional resources using the red arrow on the top right of this page).

 

Not got time to watch the full video? Go to the video highlights: Highlights: Precision oncology in practice- testing through to treatment in lung and prostate cancer.

 

Clinical Takeaways

  • Molecular testing with next-generation sequencing of DNA and RNA should be considered standard of care where possible using high-quality, sufficient tissue samples for accurate biomarker testing
  • Pathologists should conduct ‘reflex testing’ after histologic diagnosis of lung cancer, and liquid biopsies should be utilised as a complementary testing method or when tumour tissue is not feasible
  • Germline and somatic genetic testing in advanced prostate cancer may identify patients with HRR mutations and MSI-H who could be suitable for highly effective targeted agents
  • Multidisciplinary team or molecular tumour board discussion can facilitate interpretation of biomarker data, leading to more accurate patient stratification, treatment selection, and clinical decision-making

Educational objectives

  • Know how to address pre-analytical phase challenges and how to collect, store, process and prepare the samples
  • Have an awareness of which biomarkers and tests to request
  • Understand the diagnostic modalities and the role of biomarkers in oncology
  • Be able to implement or improve the leading role of the pathologist on the MDT 

Fernando Lopez-Rios is the Chief of the Molecular Diagnostics Service at Hospital Universitario 12 de Octubre (Madrid) and Professor of Pathology at Universidad Complutense (Madrid).

 

Dr Lopez-Rios has also been the Director of the Therapeutic Targets Laboratory at HM Hospitales (Spain) and a visiting researcher at Memorial Sloan Kettering Cancer Center (New York).

 

He is the 2023 recipient of the Mary J. Matthews Pathology & Transitional Research Award (International Association for the Study of Lung Cancer, IASLC) and the Deputy Chair of the IASLC Pathology Committee.

 

His main clinical and research expertise is in cancer biomarker testing.

Prof. Fernando López-Ríos, MD, PhD has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

AstraZeneca, Bayer, BMS, Lilly, MSD, Pfizer, Roche, Takeda and Thermo Fisher. 

 

Dr Morgans is Genitourinary Medical Oncologist at Dana-Farber Cancer Institute, and Faculty in Medicine at Harvard Medical School in Boston, MA. She completed medical school and residency at the University of Pennsylvania School of Medicine, fellowship in Hematology/Oncology at Harvard’s Dana Farber Cancer Institute and Massachusetts General Hospital Cancer Center in Boston and earned a Master of Public Health at Vanderbilt University. Dr Morgans treats patients with prostate, bladder, and testicular cancer, and her research assesses complications of advanced prostate cancer survivorship and patient-centered treatment decision-making in advanced prostate cancer.

Assoc. Prof. Alicia Morgans has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

AAA, Astellas, AstraZeneca, Bayer, Exelixis, Janssen, Myovant, Novartis, Pfizer, Sanofi and Telix. 

Dr Herbert H. Loong holds conjoint appointments of Clinical Associate Professor in the Department of Clinical Oncology and Deputy Medical Director of the Phase 1 Clinical Trials Centre of The Chinese University of Hong Kong.

 

Dr Loong obtained his medical degree with a Distinction in Surgery from The University of Hong Kong in 2003. He has completed a Fellowship in Drug Development at Princess Margaret Cancer Centre in Toronto, Canada with a focus on Experimental Therapeutics. His clinical and research interests include Thoracic Oncology, Sarcoma Medical Oncology and Health Economics.

 

Dr Loong is a recipient of the European Cancer Congress Fellowship Grant (2013), the American Society of Clinical Oncology (ASCO) Annual Meeting Merit Award (2014), the Hong Kong College of Physicians Young Investigators’ Award (2014). Dr. Loong led the Lung Cancer Team at CUHK to be bestowed the IASLC Foundation Cancer Care Team Award in recognition for providing the best thoracic oncology care in “Asia & Rest of the World” in 2018.

 

In recent years, Dr Loong has co-founded the Asia Pacific Oncology Drug Development Consortium (APODDC) and the Asia Pacific Coalition Against Lung Cancer (APCLC).

 

Dr Loong has served or continues to serve in various capacities in various professional international oncology bodies, including the International Affairs Committee and the Asia-Pacific Regional Council of ASCO, the Membership, Education and Communications Committees of the IASLC. He is the incoming Chairman of the International Affairs Committee of ASCO in 2024. He has been elected as a Board Member of the Connective Tissue Oncology Society (CTOS) for 2022-2024. In his prior appointment as a member of Pharmacy and Poisons Board of Hong Kong, he oversaw the registration of medicinal products and clinical trials in the territory.

Dr Herbert H. Loong has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

AbbVie, Amgen, Bayer, Boehringer-Ingelheim, Celgene, Eisai, Eli-Lilly, George Clinical, Guardant Health, Illumina, Janssen, Novartis, Merck Sereno, Pfizer, Takeda

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This educational programme is supported by an Independent Educational Grant from AstraZeneca and Amoy Diagnostics.
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PRECISION ONCOLOGY CONNECT is an initiative of COR2ED, supported by Independent Educational Grants from AstraZeneca, Amoy Diagnostics, Bayer, Pierre Fabre Laboratories and Thermo Fisher Scientific.

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LUNG CONNECT is an initiative of COR2ED, supported by Independent Educational Grants from Bayer, Pierre Fabre Laboratories and Boehringer Ingelheim.

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GU CONNECT is an initiative of COR2ED, supported by Independent Educational Grants from AstraZeneca, Bayer and Eisai Europe Limited.

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Share this programme
This educational programme is supported by an Independent Educational Grant from AstraZeneca and Amoy Diagnostics.
Supporter Acknowledgement
This educational programme is supported by an Independent Educational Grant from AstraZeneca and Amoy Diagnostics.
Endorsement
I agree that this educational programme:

Was valuable to me

1/4
Brought to you by
PRECISION ONCOLOGY CONNECT

PRECISION ONCOLOGY CONNECT is an initiative of COR2ED, supported by Independent Educational Grants from AstraZeneca, Amoy Diagnostics, Bayer, Pierre Fabre Laboratories and Thermo Fisher Scientific.

Meet the experts
Brought to you by
LUNG CONNECT

LUNG CONNECT is an initiative of COR2ED, supported by Independent Educational Grants from Bayer, Pierre Fabre Laboratories and Boehringer Ingelheim.

Meet the experts
Brought to you by
GU CONNECT

GU CONNECT is an initiative of COR2ED, supported by Independent Educational Grants from AstraZeneca, Bayer and Eisai Europe Limited.

Meet the experts Independent IME approved

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