Diagnosis and Management of Bone Sarcoma

A medical oncologist, Silvia Stacchiotti works in the Adult Mesenchymal and Rare Tumor Medical Treatment Unit, Cancer Medicine Department, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milano, Italy. Dr Silvia Stacchiotti received his medical degree in 1993 in Milan, and trained at the INT. She is board certified in Medical Oncology. She has four children. She is involved in all institutional research activities on adult bone and soft tissue sarcomas (STS), including GIST. This includes neoadjuvant therapies in extremities and retroperitoneal STS, identification of new targets and new anticancer treatments for specific sarcoma types, studies on the immune-profile of sarcomas as well as on mechanisms of resistance to therapy and the development of preclinical models of sarcomas. She collaborates to the Italian Network on Rare Tumors. She is particularly dedicated to ultra-rare sarcomas, among which chordoma, chondrosarcoma, giant cell tumor of the bone, extraskeletal myxoid chondrosarcoma, alveolar soft part sarcoma, clear cell sarcoma, dermatofibrosarcoma protuberans, solitary fibrous tumor, PEComa, vascular tumors, epithelioid sarcoma, desmoid tumor, tenosynovial giant cell tumor. She is the Principal Investigator of several Italian and International trials on sarcomas. She is the current president of the Italian Sarcoma Group (ISG). She is the faculty coordinator of the Sarcoma track of the European Society for Medical Oncology (ESMO) and the subject editor of the ESMO guidelines committee for sarcoma and GIST. She is a member of the Board of Directors of the Connective Tissue Oncology Society (CTOS). She is included in the list of European Medical Agency (EMA) external experts. She is the chair of the systemic therapy subcommittee of the EORTC Soft Tissue and Bone Sarcoma Group. She collaborates with several sarcoma Patients Advocacy Groups, among which the Chordoma Foundation, the Desmoid Tumor Research Foundation, the EHE Foundation, in which she serves as a member of the respective medical advisory boards. She has authored more than 200 scientific publications. She serves on the editorial board of European Journal of Cancer and Cancer

Prof. Silvia Stacchiotti has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

Aadi, Amgen Dompé,  Advenchen, Astex Pharmaceuticals, Bayer, Bavarian, Blueprint, Deciphera, Eli Lilly, Epizyme Inc., Dalichi Sankyo, Glaxo Smith Kline, Hutchinson, Ikena, Karyopharm, Maxivax, Novatis, Pfizer, PharmaMar, Rain Therapeutic and SpringWorks. 

Florence Duffaud (MD, PhD) underwent medical training and completed her medical oncology fellowship and residency at the University of Medicine of Marseilles, France. She completed a one-year fellowship at the EORTC data centre in Brussels. She is currently a Professor of Oncology at the University of Medicine of Marseilles, at Aix-Marseilles University (AMU), and the head of the medical Oncology Unit at La Timone University Hospital, in Marseilles. Her research interests are focused on novel therapies, and novel therapeutic strategies on soft tissues sarcoma, bone sarcoma and GISTs. She has led and/or developed multiple investigational clinical trials for soft tissues and bone sarcomas and GISTs as, principal investigator or site principal investigator. She serves on the French Sarcoma Group (FSG) board and is a member of the FSG and of the soft tissue and bone sarcoma group (STBSG) of the EORTC. She is reviewer for several oncological journals.