In video 1, you'll hear about 1st line chemotherapy options, drawing on data from key clinical trials, as well as considering the role of targeted therapy, where appropriate.
Video 2 addresses 2nd line chemotherapy options and how earlier treatments have an impact on treatment sequence.
You can also download the accompanying slides for each video for more details. Coming soon: a short accredited assessment to test your knowledge.
Clinical takeaways
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Pancreatic ductal adenocarcinoma (PDAC) is usually diagnosed at an advanced, incurable stage due to non-specific symptoms and has an extremely poor prognosis
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Systemic chemotherapy is the standard treatment for metastatic PDAC, but molecularly targeted treatments and immunotherapies may have a role for specific patients
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Treatment selection depends on several factors, including patients' performance status and co-morbidities. These should be considered alongside the efficacy and safety profiles of the different chemotherapy regimens
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Treatment strategies can be implemented to manage toxicities associated with the different chemotherapy regimens to enable a patient to stay on treatment for optimal efficacy