To mark Breast Cancer Awareness Month, we are pleased to share an animated video on treating metastatic breast cancer from Prof. Francois-Clement Bidard.

 

Explore how to optimise treatment selection and make appropriate sequencing decisions for patients with ER+/HER2- metastatic breast cancer, as Prof. Bidard explains:

  • Why we should determine molecular characteristics for each patient
  • When to perform ESR1 mutation testing
  • Current treatment guidelines for ER+ metastatic breast cancer

Watch the video and download the accompanying slides below.

 

Marking Breast Cancer Awareness Month

 

Clinical Takeaways

  • To optimise treatment selection, molecular characterization should be conducted for each patient

  • ESR1 mutation testing should preferably be performed using a liquid biopsy platform when recurrence or progression occurs during endocrine therapy

  • Elacestrant was the 1st oral SERD to be FDA approved (January 2023), with optimal efficacy and manageable safety for patients with ESR1 mutated ER+/HER2- advanced or metastatic breast cancer

  • Oral SERDs are being studied as a monotherapy and in combination with targeted therapies, offering promising prospects for their integration into clinical practice

  • Recognise the efficacy and safety profiles of SERDs for patients with advanced or metastatic BC, and understand their place in the treatment landscape for patients with BC
  • Implement optimization of treatment selection, and make the appropriate sequencing decisions
  • Be able to identify and manage adverse events

François-Clément Bidard, MD PhD, is a Professor of Medical Oncology in Paris and Saint-Cloud, France. His clinical work is dedicated to breast cancer care, whereas his translational and clinical research focuses on all forms of liquid biopsy and new therapies to move ahead of cancer resistance.

Prof. François-Clément Bidard has received financial support/sponsorship for research support, consultation, or speaker fees from the following companies:

Prof. Bidart discloses financial support/sponsorship from AstraZeneca, Daiichi-Sankyo, Caris, Exact Sciences, General Electrics Healthcare, GSK, Inatherys, Lilly, Merck KGaA, Menarini Silicon Biosystems, Menarini/Stemline, Novartis, Pfizer, Prolynx, Rain Oncology, Roche, SAGA Diagnostics, Seagen, Sanofi

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This educational programme is supported by an Independent Educational Grant from Menarini Stemline Oncology.
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BREAST CANCER CONNECT is an initiative of COR2ED, supported by an Independent Educational Grant from Menarini Stemline Oncology, AstraZeneca and Thermo Fisher Scientific.

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