In this micro e-learning programme, you'll learn about PARP inhibitors in prostate cancer from independent experts Assoc. Prof. Alicia Morgans and Dr Pasquale Rescigno. 

Module 1 covers the use of PARP inhibitors as monotherapy in advanced prostate cancer, and in module 2, the experts will explore the rationale behind combination treatment with anti-androgens. After watching the videos, take the assessments to earn your CME credit.

Clinical takeaways:

• PARP inhibitors are effective drugs as monotherapy in mCRPC patients with HRR alterations
• Genetic testing is important to help with treatment decision-making and for understanding inherited risk
• BRCA mutations are associated with poor outcomes in mCRPC patients
• Patients with tumours harbouring BRCA1/BRCA2 alterations appear to derive the greatest clinical benefit from PARPi, but patients with other HRR alterations also derive benefit
• PARP inhibitors combined with novel hormonal agents are effective as a first-line treatment option for mCRPC patients with an HRR mutation. Certain combinations, such as olaparib plus abiraterone, have also shown benefits in patients regardless of their HRR status

This PARP Inhibitors in Prostate Cancer micro e-learning programme is endorsed by