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Follow a patient's journey through advanced HCC and make decisions on treatment selection and sequencing in this interactive patient case video presented by Prof. Dr Timon Vandamme.

 

As you interact and engage with valuable information, challenging questions, and clickable resources, you'll choose your preferred 1st line treatment option for this patient, when to switch to 2nd line treatment, and which 2nd line option to recommend.

 

Clinical Takeaways

  • IO based treatments are the first choice for patients with advanced HCC without active auto-immune disease and without liver transplant
  • In case of slow progression, continuing IO based treatment should be considered for patients with HCC
  • Research is ongoing to determine the best treatment options and sequencing after progression on IO based treatment for patients with HCC

Educational Objectives

  • Understand the systemic treatment options for patients with advanced and intermediate HCC
  • Know the treatment options for patients with advanced HCC not eligible for immunotherapy in 1st line
  • Know the right time to switch to 2nd line therapy (including progression and patient evaluation, such as liver function) and implement optimal sequencing

Timon Vandamme is a Senior Consultant in digestive and neuroendocrine oncology at the Antwerp University Hospital. As a clinician-researcher, he is performing research in circulating cell-free DNA (ccfDNA) in digestive and neuroendocrine neoplasms.

 

Dr Vandamme obtained a joint PhD at the University of Antwerp, Belgium and the Erasmus MC, the Netherlands, on preclinical and translation evaluation of everolimus resistance and pancreatic NET genomics. His PhD project has led to multiple publications in peer-reviewed journals and received numerous awards, both national and international. Currently, he is holder of a Senior Clinical Investigator (FKM) grant of the Fonds Wetenschappelijk Onderzoek (FWO) at the University of Antwerp.

 

Furthermore, he is the Principal Investigator (PI) of > 10 trials at the University Hospital Antwerp, both industry-sponsored and academic trials. He is promotor of four PhD students and mentor of two additional PhD students. He has authored numerous papers outside his PhD in journals such as Clinical Cancer Research and Lancet Oncology. He has peer-reviewed for different high-impact journals and is a member of the editorial board of Endocrine-Related Cancer.

He is currently acting secretary of the Dutch Belgian Neuroendocrine Tumor Society (DBNETS) and co-opted board member of the Belgian Group of Digestive Oncology (BGDO). In addition, he is active member of the EORTC GI Tract Cancer Group and the ENETS Translational Working Group.

 

Programme summary
  • clock Duration 15 MIN
  • clock Language(s) flag
Other episodes in this series
Advanced HCC: When to switch to 2nd line treatment

Advanced HCC: When to switch to 2nd line treatment

Explore treatment selection and optimal sequencing after progression on immunotherapy in an interactive patient case video

Current Episode
Advanced HCC: Treatment options for patients ineligible for IO

Advanced HCC: Treatment options for patients ineligible for IO

Explore treatment options, adverse event management and next steps in this interactive patient case

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This educational programme is supported by an Independent Medical Education Grant from Bayer.
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HCC CONNECT is an initiative of COR2ED, supported by an Independent Educational Grant from Bayer, AstraZeneca and Eisai Europe Limited.

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