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The Use of Immunotherapy in HCC: Efficacy and Safety

The Use of Immunotherapy in HCC: Efficacy and Safety

A micro learning programme for GI and liver specialists

A micro learning programme for GI and liver specialists

Prof. Dr Peter R. Galle, Dr Aiwu Ruth He

In Module 1 of this micro learning, developed by experts Prof. Peter R. Galle and Dr Aiwu Ruth He, you'll learn about the safety and efficacy of immunotherapy (IO) for hepatocellular carcinoma (HCC) and how to implement IO treatments for patients with HCC in clinical practice.

The content includes a short animated video, downloadable resources, and an assessment to test your knowledge.

Module 2, coming soon, will focus on in-depth subgroup analyses and challenges.


Efficacy of IO for HCC

Learn how to:

  • Recognise the efficacy of IO and IO combinations
  • Understand the survival curve when assessing IO treatment
  • Know where IO and IO combinations sit in the treatment landscape for patients with HCC


Safety of IO for HCC

Learn how to:

  • Recognise the immune-related adverse events (irAEs) and potential additive or synergistic toxicities associated with IO combinations
  • Know how to identify and manage these AEs early on
Prof. Dr Peter R. Galle


University Medical Centre Mainz


Dr Aiwu Ruth He

GI Medical Oncologist

Medstar Georgetown University Hospital

United States (US)

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The use of immunotherapy in HCC - efficacy and safety

time Micro learning | open 4 min | May 2023

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Clinical Takeaways


  • IO, and in particular IO combinations, are effective treatments for patients with advanced HCC

  • Survival analysis for IO treatment shifts from median overall survival (OS) to landmark analysis

  • IO and IO combinations may result in inflammatory side effects, known as irAEs. Most of these AEs can be treated with steroids


This programme is endorsed by:


Digestive Cancers Europe (DiCE) is the European umbrella organisation of a large group of national members representing patients with digestive cancer – colorectal, gastric, liver, oesophageal, pancreatic and rare cancers. Our mission is to contribute to early diagnosis and decreased mortality from digestive cancers and to increase overall survival and quality of life.

DiCE is running a survey to map the availability of liver cancer treatments across the EU. The aim is to aid broader access to best-practice care to ultimately increase liver cancer survival rates across Europe. Can you spare 15 minutes to share what treatments are available in your EU country? Take the survey.


AASLD is a leading organization of scientists and healthcare professionals committed to preventing and curing liver disease. We foster research that leads to improved treatment options for millions of liver disease patients. We advance the science and practice of hepatology through educational conferences, training programmes, professional publications, and partnerships with government agencies and sister societies.


This educational programme is supported by an Independent Medical Education Grant from AstraZeneca

HCC CONNECT is an initiative of COR2ED, supported by an Independent Educational Grant from Bayer, AstraZeneca and from Eisai Europe Limited.

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