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This educational programme is supported by an Independent Medical Education Grant from Viatris.

In this final episode in a 4-part series on thrombosis in different clinical situations, medical experts discuss the current approaches to perioperative thromboprophylaxis. They explore the pathophysiology of perioperative thrombosis, special considerations, and how to apply perioperative thromboprophylaxis in practice, including thrombotic and bleeding risk stratification, choosing an anticoagulant, and the ideal duration of postoperative thromboprophylaxis.

 

E-learning

After listening to the podcast series, take the e-learning assessment to test your knowledge and earn CME credits.

 

Clinical Takeaways

  • Thrombotic risk is a constant threat in postoperative patients but has decreased with the evolution of surgical technology
  • A shift from low molecular weight heparins (LMWHs) to direct oral anticoagulants (DOACs) and from short to longer duration has been established in the guidelines in the last few years
  • In major orthopedic surgery, aspirin 100mg/d can be used as an alternative if there is a low risk of VTE and if DOACs are not applicable or in cases of high risk for bleeding
  • Thromboembolic complications should still be considered since they may affect morbidity and mortality after surgery

Educational objectives

  • Understand the pathophysiology of perioperative thrombosis
  • Learn how to apply perioperative thromboprophylaxis, i.e. thrombotic and bleeding risk stratification, choice of anticoagulant and the duration of postoperative thromboprophylaxis
  • Learn new insights from experts discussing special considerations in perioperative thrombosis

Prof. Dimitrios A. Tsakiris, MD was born in Thessaloniki, Greece and obtained his Diploma of Medicine (1982) at the Medical School, Aristotle University of Thessaloniki, Greece. He started his training in Clinical Haematology at the AHEPA University Hospital in Thessaloniki and completed it at the University Hospital Basel in Basel, Switzerland, where he has been working since 1987. He holds a license for Clinical Haematology and Laboratory Haematology. He spent one year (1996) as a Research Associate in Platelet Research at the Mount Sinai School of Medicine, New York, NY, USA. He has held a professorship in Haematology at the Faculty of Medicine, University of Basel, Switzerland since 2004 and serves also as a visiting Professor of Hematology at the Medical School of the Aristotle University of Thessaloniki. He has served as Head of Haemostasis since 2009 and Head of Diagnostic Haematology and Haemostasis (2014-2021), as well as member of the Stem Cell Transplant and Cell-Therapy Center Basel at the University Hospital Basel, Switzerland. Since 2021 he has been Director of Thrombosis and Haemostasis and Co-Head Hematology at SYNLAB Suisse SA, Switzerland. His main fields of scientific interests are platelet activation, platelet disorders, diagnosis and treatment of bleeding disorders and thrombophilia, disorders of haemostasis and endothelial cells after stem cell transplants. He has presented over 140 peer-reviewed original articles and reviews.

Daniel Bolliger received his medical degree from Basel University, Switzerland, in 1998. He finished his anesthesiology training at Basel University Hospital and different smaller hospitals in Switzerland in 2011. In parallel to his clinical training, he started his full time research activity at the University Hospital of Basel, Switzerland, and later at Emory University, Atlanta, USA. In 2011, he received the venia docendi, and in 2018, he became Professor at the Medical Faculty, University of Basel.

 

Since 2011, Daniel Bolliger has been staff member at the Department of Anesthesiology, University Hospital Basel. He mainly works in cardiac, vascular and thoracic anesthesia. Since 2017, he has been head of non-operating room anesthesia (NORA) and responsible anesthesist for the emergency room. Further, he developed large parts of the patient blood management at his department.

 

Dr Bolliger has been actively involved with many preclinical and clinical studies in hemostasis and thrombosis in surgical and critically ill patients. Further studies covered the topic of the predictive value of cardiac biomarkers in patients undergoing cardiac and non-cardiac surgery. Finally, he also performed several studies and projects with intraoperative echocardiography. He has authored more than 130 peer-reviewed journal articles in addition to several review articles and book chapters. Further, he has contributed as a reviewer for various prestigious journals and is associate editorial board member of the Journal of Cardiothoracic and Vascular Anesthesia. He has lectured on the mechanisms of perioperative coagulopathy, and methods of point-of-care hemostatic diagnostics in cardiac and non-cardiac surgical procedures at various national and international meetings.

Programme summary
Listen to the podcast now
Other episodes in this series
Monitoring Anticoagulation: Yes or No?

Monitoring Anticoagulation: Yes or No?

A clinical discussion on anticoagulation monitoring

Cancer and Thrombosis

Cancer and Thrombosis

A podcast discussion on treating thrombosis in patients with cancer

VTE: What is the optimal duration of antithrombotic treatment?

VTE: What is the optimal duration of antithrombotic treatment?

Part 3 of a 4-part series on thrombosis

Perioperative thromboprophylaxis revisited

Perioperative thromboprophylaxis revisited

Minimising the risk of thrombosis in surgical patients

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HEMOSTASIS CONNECT is an initiative of COR2ED, supported by an Independent Educational Grant from Pfizer, Sobi, Takeda, Viatris and Pentapharm.

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