Director of the Israel National Haemophilia Centre and Thrombosis Institute, Sheba Medical Centre and Director of Amalia Biron Research Institute of Thrombosis and Haemostasis, Tel Aviv University (located at the Sheba Medical Centre). Gili Kenet is a paediatric haematologist, Professor and former Chair of the Haematology Department at the Sackler Medical School, Tel Aviv University. Professor Kenet received her Medical Degree from the Hebrew University in Jerusalem. Her research projects have been focused on neonatal haemostasis, childhood stroke and paediatric thrombophilia, as well as the research of new therapy modes applied for people with haemophilia and severe bleeding disorders. She was awarded national grants for paediatric haematology and cancer research, study of rFVIIa mode of action, epidemiology of inhibitor evolution in haemophilia and for personalised tailoring of bypass agent therapy, and applying global haemostasis assays. Prof. Kenet pioneered in gene therapy clinical trials in Israel and novel non replacement drugs in haemophilia. Professor Kenet is the author of over 200 peer reviewed scientific publications, review articles and book chapters. An active member of the World Federation of Haemophilia, Israeli Society of Paediatric Haematology and Oncology, and the American Society of Haematology, an active reviewer for high impact thrombosis journals and an editorial board member of the Haemophilia journal. Former Chairperson of the Israeli Society of Thrombosis and Haemostasis and Chairperson of the Paediatric and Peri-natal Haemostasis Scientific Subcommittee of ISTH. Currently co-chairs the FVIII/FIX and rare bleeding disorders of the SSC of ISTH.

Jan Blatný, MD, PhD, is Consultant Haematologist at the Department of Paediatric Haematology, Centre for Thrombosis and Haemostasis, Director of the Haemophilia Comprehensive Care Centre and Medical Director for Paediatrics of University Hospital in Brno, Czech Republic. He is also an Associate Professor of Paediatrics at Masaryk University in Brno, Czech Republic. His research interests encompass paediatric haematology, thrombosis and haemostasis, and life-threatening bleeding. He is a member of the Working Party on population PK of the ISTH SSC Subcommittee on Factor VIII and IX and Rare Bleeding Disorders. In addition to ISTH, Dr Blatný is a member of numerous national and international haematology organizations. He serves on the steering committee and is a paediatric coordinator of the Czech National Haemophilia Programme, member of Executive Committee of EAHAD, member of MAG (Medical advisory group) of EHC, a reviewer for several haematology journals, and is on the editorial board for an official journal of Czech Haematology society. From November 2020 - April 2021 he served as a Minister of Health of The Czech Republic. Dr Blatný’s publication credits are 9 book chapters and over 80 articles published in peer-reviewed journals.

Maria Elisa Mancuso MD, PhD is a Senior Consultant in Haematology with a special interest in haemostasis. She obtained a post-degree in Clinical and Experimental Haematology and a PhD in Clinical Methodology. She worked as a Clinical Assistant at the Angelo Bianchi Bonomi Hemophilia and Thrombosis Center in Milan (Italy) from 2008 to 2020. Since May 2020 she has been Senior Consultant at the Center for Thrombosis and Haemorrhagic Diseases at IRCCS Humanitas Research Center in Rozzano, Milan (Italy). Dr Mancuso is involved in clinical research and has published several original articles in peer-reviewed journals such as The Lancet, Blood, Journal of Thrombosis and Haemostasis, Haematologica, Thrombosis and Haemostasis, British Journal of Haematology and Haemophilia. She is a member of the Editorial Board of the Journal of Thrombosis and Haemostasis and is a reviewer for several peer-reviewed journals in the field of Thrombosis and Haemostasis and is a member of several national and international scientific societies (AICE, SISET, ISTH, WFH, ASH, EAHAD). She has acted as Co-Chair of the Scientific and Standardization Subcommittee of ISTH (SSC-ISTH) on FVIII, FIX and rare bleeding disorders. Dr Mancuso has been involved as co-investigator in several clinical trials, and takes care of both children and adults with haemophilia with a specific scientific interest in inhibitors, chronic hepatitis C, optimisation of prophylaxis and novel therapies.

Kaan Kavakli, MD, is chair of the Department of Paediatrics and a professor of paediatrics and paediatric haematology at the Medical School of Ege University in Izmir, Turkey, where he previously was chair of the Department of Paediatric Haematology. Additionally, he is a paediatric haematologist in the Department of Paediatrics at Ege University Hospital and the director of the Ege Haemophilia Centre and the Ege Haemophilia Association. Dr Kavakli received his medical degree and training in paediatrics at Ege University Medical School. His special interests are haemostasis, thrombosis, and the care of patients with haemophilia. His recent work has included identification of certain mutations in Turkish haemophilia patients with inhibitors, radioisotope synovectomy for haemophilic arthropathy, the role of circumcision in boys with haemophilia, and treatment options for patients with inhibitors. Dr Kavakli has been a principal investigator for international clinical trials in haemophilia. Dr Kavakli is president of the Turkish Hemostasis and Thrombosis Association and the Hemophilia Federation of Turkey, which comprises 11 regional haemophilia associations. He is a member of many international societies and serves on the editorial boards and as a reviewer for several haematology journals. Dr Kavakli has published more than 100 papers in such journals as Blood, The New England Journal of Medicine, and Haemophilia, etc.